Ahmet Hoke - Recent Papers

 Mathews, D,J,, Sugarman, J., Bok, H., Blass, D.M., Coyle, J.T., Duggan, P., Finkel, J., Greely H.T., Hillis, A., Höke, A., Johnson, R., Kahn, J., Kerr, D., Kurtzberg, J., Liao, S.M., McDonald, J.W., McKahn, G., Nelson K.B., Rao, M., Regenberg A., Siegel A.W., Smith, K., Solter, D., Song, H., Vescovi, A., Young, W. Gearhart, J.D., Faden, R., (2008) “Cell-based interventions for neurologic conditions. Ethical challenges for early human trials” Neurology Epub ahead of print May 7, 2008

Toth, C., Martinez J.A., Diggle J., Fang, Q., Ramji, N., Mi, R., Höke, A., Zochodne, D.W. (2008) “Local erythropoietin signalling enhances regeneration in peripheral axons”, Neuroscience Epub ahead of print March 29, 2008

Laird, F., Farah, M., Ackerley, S., Höke, A., Maragakis, N.J., Rothstein, J.D., Griffin, J.W., Price, D., Lee, M., Wong, P. (2008) “Mutant dynactin p150Glued causes motor neuron disease characterized by defects in vesicular trafficking”, J. Neurosci Vol: 28(9), pp: 1997-2005

Chandran, J.S., Lin, X., Zapata, A., Höke, A., Shimoji, M., Moore, S.O., Galloway, M.P., Laird, F.M., Wong, P.C., Price, D.L., Bailey, K.R., Crawley, J.N., Shippenberg, T., Cai. H. (2008) “Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function”, Neurobiol Dis Vol: 29(3), pp: 505-514

Milward, E., Kim, K.J., Szklarczyk, A., Nguyen, T., Melli, G., Nayak, M., Deshpande, D., Fitzsimmons, C., Höke, A., Kerr, D., Griffin, J.W., Calabresi, P.A., Conant, K. (2008) “Cleavage of myelin associated glycoprotein by matrix metalloproteinases”, J Neuroimmunol Vol: 193(1-2), pp: 140-8

Lagoda G., Sezen S.F., Liu T., Höke A., Burnett A.L. (2008) “FK506-binding protein localizations in human penile innervation”, BJU International. Vol: 101(5), pp:604-9

Chew, S.Y., Mi, R., Höke, A., and Leong, K. (2008) “The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation”, Biomaterials Vol: 29(6), pp:653-61

Zhu Y., Antony J.M., Martinez J.A., Glerum D.M., Brussee V., Höke A., Zochodne D. and Power C. (2007) “Didanosine causes sensory neuropathy in an HIV/AIDS animal model: impaired mitochondrial and neurotrophic factor gene expression”, Brain. Vol: 130(8), pp: 2011-23

Chew, S.Y., Mi, R., Höke, A., and Leong, K. (2007) “Aligned Protein-Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue-Engineering Platform”, Advanced Functional Materials, Vol:17, pp:1288-1296

Chen, W., Mi, R., Haughey, N., Oz, M. and Höke, A. (2007) “Immortalization and characterization of a nociceptive dorsal root ganglion sensory neuronal line”, JPNS, Vol:12(2), pp:121-130

Mi, R., Chen, W. and Höke, A. (2007) “Pleiotrophin is a neurotrophic factor for motor neurons”, PNAS, Vol: 104(11), pp: 4664-9

Valentine H, Chen Y, Guo H, McCormick J, Wu Y, Sezen SF, Höke A, Burnett AL, Steiner JP (2007) “Neuroimmunophilin Ligands Protect Cavernous Nerves after Crush Injury in the Rat: New Experimental Paradigms”,  Eur Urol, Vol:51(6), pp:1724-31

Cheepudomwit T, Güzelsu E, Zhou C, Griffin JW, Höke A (2008) “Comparison of cytokine expression profile during Wallerian degeneration of myelinated and unmyelinated peripheral axons”, Neurosci Lett, Vol:430(3), pp:230-5

Höke, A., Redett, R., Hameed, H., Jari, R., Zhou, C., Li, Z.b., Griffin, J.W., and Brushart, T.M. (2006) “Schwann cells express motor and sensory phenotypes that regulate axon regeneration”, J Neurosci Vol: 26(38), pp: 9646-55

Pettersen, J.A., Jones, G., Worthington, C., Krentz, H.B., Keppler, O.T., Hoke, A., Gill, M.J. and Power, C.  (2006)  Sensory Neuropathy in Human Immuno deficiency Virus/Acquired Immunodeficience Syndrome Patients:  Protease Inhibitor-Mediated Neurotoxicity.  Ann Neurol 59:816-824.  [PDF]

Hoke, A. (2006)  Mechanisms of Disease:  What factors limit the success of peripheral nerve regeneration in humans? Nature Review 2(8): 448-450.  [PDF]

Melli, G., Jack, C., Lambrionos, G.L., Ringkamp, M. and Hoke, A.  (2006)   Erythropoietin protects sensory axons against paclitaxel-induced distal degeneration.  Neurobiology of Disease doi:10:1016/j.nbd.2006.08.014. [PDF]

Keswani, S.C., Jack, C., Zhou, C. and Hoke, A.  (2006)  Establishment of a Rodent Model of HIV-Associated Sensory Neuropathy. J Neuroscience 26(40);10299-10304.   [PDF]

Cornblath, D.R. and Hoke, A.  (2006)  Recent Advances in HIV neuropathy.  Current Opinion in Neurology 19:446-450.  [PDF]

Hoke, A., Redett. R., Hameet, H., Jari, R., Zhou, C., Li, Z.B.,  Griffin, J.W. and Brushart, T.M.  (2006)  Schwann Cells Express Motor and Sensory Phenotypes That Regulate Axon Regeneration.  Journal of Neuroscience 26(38):9646-9655.  [PDF]

Melli, G., Keswani, S.C., Fischer, A., Chen, W. and Hoke, A.  (2006)  Spatially distinct and functionally independent mechanism of axonal degeneration in a model of HIV-associated sensory neuropathy.  Brain 129:1330-1338.  [PDF]

Deshpande, D.M., Mbiot, MS, Kim, Y-S, Martinez, T., Carmen, J., Dike, S., Shats,R., Rubin, L.L., Drummond, J., Krishnan, C., Hoke, A., Maragakis, N., Shefner, J., Rothstein, J.D., and Kerr, D.A.  (2006)  Recovery from Paralysis in Adult Rats Using Embryonic Stem Cells.  Ann Neurol 60:32-44.  [PDF]

Cai, H., Lin, X., Xie, C., Laird, F.M., Lai, C., Wen, H., Chiang, H-C., Shim, H., Höke, A., Price, D.L., and Wong, P.C. (2005) “Motor coordination and earning deficits, increased anxiety, and susceptibility to oxidative stress in mice lacking ALS2”, Journal of Neuroscience, Vol: 25(33), pp: 7567-74

Mi, R., Luo, Y., Cai, J., Limke, T. L., Rao, M. S., and Höke, A. (2005) “Immortalized neural stem cells differ from non-immortalized cortical neurospheres and cerebellar granule cell progenitors ”, Exp Neurol, Vol: 194(2), pp: 301-19  [PDF]

Keswani, S., Buldanlioglu, U., Fischer, A., Reed, N., Polley, M., Liang, H., Zhoi, C., Jack, C., Leitz, G.J. and Höke, A. (2004) “A novel endogenous erythropoietin mediated pathway prevents axonal degeneration” Annals of Neurology,  Vol: 56(6), pp: 815-26  [PDF]

Heine, W., Conant, K., Griffin, J.W., and Höke, A. (2004) “Transplanted neural stem cells promote axonal regeneration through chronically denervated peripheral nerves”, Exp Neurol, Vol: 189 (2), pp: 231-240  [PDF]

Keswani, S., Polley, M., Pardo, C., McArthur, J.C., Griffin, J.W. and Höke, A. (2003) “Schwann cell chemokine receptors mediate HIV-1 gp120 toxicity to sensory neurons” Annals of Neurology, Vol: 54, pp: 287-96  [PDF]

Höke, A., Ho, T., Crawford, T. LeBel, C., Hilt, D. and Griffin, J.W. (2003) “Glial Cell Line-Derived Neurotrophic Factor Alters Axon-Schwann Cell Units and Promotes Myelination in Unmyelinated Nerve Fibers”, Journal of Neuroscience Vol: 23, pp: 561-7  [PDF]