Johns Hopkins University, Department of Neuroscience

David Ginty - Recent Papers

 

  • Riccio, A., Pierchala, B. Ciarallo, C., and Ginty, D.D. CREB is a target of an NGF-TrkA dependent retrograde signal in sympathetic neurons. Science, 277:1097-1100, 1997. [PDF]

 

  • Kolodkin, A.L, Levengood, D.V., Rowe, E., Tai, Y.-T., Giger, R. and Ginty, D.D. Neuropilin is a Semaphorin III receptor. Cell, 90:753-762, 1997. [PDF]

 

  • Qian, X., Zhang, Y., Riccio, A., and Ginty, D.D. Identification and characterization of novel substrates of Trk receptors. Neuron, 21:1017-1029, 1998. [PDF]

 

  • Riccio, A., Ahn, S., Davenport, C.M., Blendy, J. and Ginty, D.D. Mediation by a CREB family transciption factor of NGF-dependent survival of sympathetic neurons. Science, 286:2358-2361, 1999. [PDF]

 

  • Kuruvilla, R., Ye, H., Ginty, D.D. Spatially and functionally distinct roles of the PI3-K effector pathway during NGF signaling in sympathetic neurons. Neuron, 27:499-512, 2000. [PDF]

 

  • Cloutier, J.F., Giger, R.J., Koentges, G., Dulac, C., Kolodkin, A.L., and Ginty, D.D. Neuropilin-2 mediates axonal fasciculation, zonal segregation, but not axonal convergence, of primary accessory olfactory neurons. Neuron, 33:877-892, 2002. [PDF]

 

  • Lonze, B, Riccio, A. Cohen, S. and Ginty, D.D. Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB. Neuron, 34:371-385, 2002. [PDF]

 

  • Ye, H., Kuruvilla, R., Zweifel, L. and Ginty, D.D. Evidence in support of signaling endosome-based retrograde survival of sympathetic neurons. Neuron, 39:57-68, 2003. [PDF]

 

  • Gu, C., Reimert, D.V., Shu, T., Frisch, B., Richards, L.J. Rodriguez, E.R., Alex L. Kolodkin, A.L. and Ginty, D.D. Neuropilin-1 conveys semaphorin and VEGF signaling during cardiovascular and neural development. Developmental Cell, 5:45-57, 2003. [PDF]

 

  • Glebova, N., and Ginty, D.D. Heterogeneous requirement of NGF for sympathetic target innervation in vivo. J. Neurosci., 24(3):743-751, 2004. [PDF]

 

  • Kuruvilla, R., Zweifel, L, Glebova, N, Lonze, B, Valdez, G., Ye, H., and Ginty, D.D. A Neurtrophin signaling cascade coodinates sympathetic neuron development through differential control of TrkA trafficking and retrograde signaling, Cell 118:243-255, 2004. [PDF] ]

 

  • Gu, C., Yoshida, Y., Livet, J., Reimert, D.V., Mann, F., Merte, J., Henderson, C.E., Jessell, T.M., Kolodkin, A.L., and Ginty, D.D. Semaphorin 3E and Plexin-D1 Control Vascular Pattern Independently of Neuropilins. Science, 307(5707):265-268, 2005. [PDF]

 

  • Ramanan, N., Shen, Y., Sarsfield, S., Lemberger, T., Schutz, G., Linden, D.J., Ginty, D.D. SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability. Nature Neuroscience. 8:759-767, 2005. [PDF]

 

  • Chen, X., Ye, H., Kuruvilla, R., Ramanan, N., Scangos, K., Zhang, C., Johnson, N., England, P., Shokat, K. and Ginty, D.D. A Chemical-Genetic Approach to Studying Neurotrophin Signaling. Neuron 46:13-21, 2005. [PDF]

  • Riccio, A., Alvania, R., Lonze, B., Ramanan, N., Kim, T., Huang, Y., Dawson, T., Snyder, S. and Ginty, D. A Nitric Oxide Signaling Pathway Controls CREB-Mediated Gene Expression in Neurons.  Molecular Cell 21:1-12, January 20, 2006.  [PDF]

 

  • Luo, W., Wickramasinghe, R., Savitt, J.M., Griffin, J.W., Dawson, T.M. and Ginty, D.D.  A Hierarchical NGF Signaling Cascade Controls Ret-Dependent and Ret-Independent Events During Development of Nonpeptidergic DRG Neurons.  Neuron 54:739-754, 2007.  [PDF]
  • Deppmann, C.D., Mihalas, S., Sharma, N., Lonze, B.E., Neibur, E., Ginty, D.D. A model for neuronal competition during development. Science320:369-373, 2008.   [PDF]
  • Makita, T., Sucov, H.M., Gariepy, C.E., Yanagisawa, M. and Ginty, D.D. Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons. Nature, 452:759-763, 2008.   [PDF]
  • Wickramasinghe, S.R., Alvania, R.S., Ramanan, N., Wood, J.N., Mandai, K., and GintyD.D. Serum Response Factor mediates NGF dependent target innervation by embryonic DRG sensory neurons. Neuron, in press.

 

© 2005 Department of Neuroscience, Johns Hopkins University School of Medicine