Figure 2. Neurons that are Preconditioned are Remarkably Resistant to Neurotoxicity and AIF does not Translocate to the Nucleus. These preconditioned cultures were exposed to neurotoxic concentrations of NMDA yet they are alive and AIF is retained in the mitochondria. New gene products regulate this profound neuronal survival.
© 2005 Department of Neuroscience, Johns Hopkins University School of Medicine