Valina Dawson - Recent Papers

Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science. 2002 Jul 12;297(5579):259-63. [PDF]

Chung KK, Zhang Y, Lim KL, Tanaka Y, Huang H, Gao J, Ross CA, Dawson VL, Dawson TM. Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat Med. 2001 Oct;7(10):1144-50. [PDF]

Nandagopal K, Dawson TM, Dawson VL. Critical role for nitric oxide signaling in cardiac and neuronal ischemic preconditioning and tolerance. J Pharmacol Exp Ther. 2001 May;297(2):474-8. [PDF]

Nucifora FC Jr, Sasaki M, Peters MF, Huang H, Cooper JK, Yamada M, Takahashi H, Tsuji S, Troncoso J, Dawson VL, Dawson TM, Ross CA. Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science. 2001 Mar 23;291(5512):2423-8. [PDF]

Hong, S.J., H. Li, K.G. Becker, V.L. Dawson, and T.M. Dawson. Identification and Analysis of Plasticity-Induced Late Response Genes (PLINGS). Proc. Natl. Acad. Sci. U.S.A., 101:2145-2150 (2004. [PDF]

Li, H., X. Gu, V.L. Dawson and T.M. Dawson. Identification of Calcium and Nitric Oxide Regulated Genes by Differential Analysis of Library Expression (DAzLE). Proc. Natl. Acad. Sci. U.S.A., 101: 647-652 (2004. [PDF]

Chung K.K., B. Thomas, X. Li, O. Pletnikova, J.C. Troncoso, L. Marsh, V.L. Dawson and T.M. Dawson. S-Nitrosylation of Parkin Regulates Ubiquitination and Compromises Parkin's Protective Function. Science 304(5675):1328-31 (2004. [PDF]

Hong, S.J., T.M. Dawson and V.L. Dawson. Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling. Trends Pharmacol. Sci. 25(5): 259-264 (2004. [PDF]

Koh David W., Lawler Ann M., Poitras Marc F., Saski Masayuki, Wattler Sigrid, Nehls Michael C., Stoger Tobias, Porier Guy G., Dawson Valina L., Dawson Ted M. Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality.  PNAS, 101: 17699-17704. [PDF]

Yu Seong-Woon, Wang Hongmin, Poitras Marc F., Coombs Carmen, Bowers William J., Federoff Howard J., Poirer Guy G., Dawson Ted M., Dawson Valina.  Mediation of Poly (ADP-Ribose) Polymerase-1-Dependant Cell Death by Apoptosis-Inducing Factor.  Science, 297:259-263. [PDF]

Wang, H., S.W. Yu, D.W. Koh, J. Lew, C. Coombs, W. Bowers, H.J. Federoff, G.G. Poirier, T.M. Dawson, and V.L. Dawson. “Apoptosis Inducing Factor (AIF) Substitutes for Caspase Executioners in N-methyl-D-aspartate Triggered Excitotoxic Neuronal Death.” J. Neurosci. 24: 10963-10973 (2004).  [PDF]

Koh, D.W., A.M. Lawler, M.F. Poitras, M. Sasaki, S. Wattler, M.C. Nehls, T. Stöger, G.G. Poirier, T.M. Dawson and V.L. Dawson.  "Failure to Degrade Poly(ADP-ribose) Causes Increased Sensitivity to Cytotoxicity and Early Embryonic Lethality.” Proc. Natl. Acad. Sci. U.S.A. 101(51): 17699-17704 (2004).  [PDF]

David, K.K., M Sasaki, S.-W. Yu, T.M. Dawson and V.L. Dawson.  “EndoG is Dispensable in Embryogenesis and Apoptosis,” Cell Death Diff. [Oct 21, 2005 Epub ahead of print] 13:1147–1155 (2006).  [PDF]

Yu, S.W., S.A. Andrabi, H. Wang, N.S. Kim, G.G. Poirier, V.L. Dawson and T.M. Dawson. “Apoptosis Inducing Factor (AIF) Mediates Poly (ADP-ribose) (PAR) Polymer Induced Cell Death” .”  Proc. Natl. Acad. Sci. U.S.A. [Epub November 20, 2006, 10.1073/pnas.0606528103] (2006).  [PDF]

Anrabi, S., N.S. Kim, S.W. Yu, N.S. Kim, H. Wang, D. Koh, M. Sasaki, J.A. Klaus, T. Otsuka, Z. Zhang, R.C. Koehler, P. Hurn, G.G. Poirier, V.L. Dawson and T.M. Dawson. “Poly (ADP-ribose) (PAR) Polymer is a Novel Death Signal.” Proc. Natl. Acad. Sci. U.S.A. [Epub November 20, 2006, 10.1073/pnas.0606526103] (2006).  [PDF]

Haince JF, Kozlov S, Ouellet ME, Dawson VL, Dawson TM, Lavin MF, Poirier GG  “Poly(ADP-ribosyl)ation is a potential modulator of DNA damage signaling.” East coast PARP 2006, Quebec Qc, Canada (2006).

Dawson, V.L., Zhikai Chi, Suk Jin Hong, Ho Chul Kang, Jianmin Zhang, Sika Zheng, and Ted M. Dawson. “Identification of New and Novel Survival Molecules Through Preconditioning.” The 26th Princeton Conference on Cerebrovascular Disease, Houston, Texas, 2008.