David Linden PhD

Professor of Neuroscience

Jin, Y., Dougherty, S.E., Wood, K., Sun, L., Cudmore, R.H., Abdalla, A., Kannan, G., Pletnikov, M., Hashemi, P. and Linden, D.J. (2016).  Regrowth of serotonin axons in the adult mouse brain following injury.  Neuron 91, 784-762.

Cudmore, R.H., Dougherty, S.E. and Linden, D.J. (2016). Cerebral vascular structure in the motor cortex of adult mice is stable and is not altered by voluntary exercise.  Journal of Cerebral Blood Flow and Metabolism, in press 

Zhang, Y.*, Cudmore, R.H.*, Lin, D.T., Linden, D.J. and Huganir, R.H. (2015).  Visualization of NMDA receptor-dependent AMPA receptor synaptic plasticity in vivo. Nature Neuroscience 18, 402-407.

Rylkova, D., Crank, A. and Linden, D.J. (2015).  Chronic in vivo imaging of ponto-cerebellar mossy fibers reveals morphological stability during whisker sensory manipulation in the adult rat.  eNeuro, ENEURO.0075-15.2015

Thomas, G.M., Hayashi, T., Huganir, R.L. and Linden, D.J. (2013).  DHHC8-dependent PICK1 palmitoylation is required for induction of cerebellar long-term synaptic depression.  Journal of Neuroscience 33, 15401-15407.

Park, J.M., Hu, J.-H., Milshteyn, A., Zhang, P.-W., Moore, C.G., Park, S., Datko, M.C., Domingo, R.D., Reyes, C.M., Wang, X.J., Etzkorn, F.A., Xiao, B., Szumlinksi, K.K., Kern, D., Linden, D.J. and Worley, P.F. (2013).  A prolyl-isomerase mediates dopamine-dependent plasticity and cocaine motor sensitization.  Cell 154, 637-650.

Kim YS, Kang E, Makino Y, Park S, Shin JH, Song H, Launay P, Linden DJ. (2013) Characterizing the conductance underlying depolarization-induced slow current in cerebellar Purkinje cells. Journal of Neurophysiology, 109(4):1174-81.

He L, Linden DJ, Sapirstein A. (2012) Astrocyte inositol triphosphate receptor type 2 and cytosolic phospholipase A2 alpha regulate arteriole responses in mouse neocortical brain slices. PLoS One 7:e42194. 

Linden D.J. (2012) A late phase of LTD in cultured cerebellar Purkinje cells requires persistent dynamin-mediated endocytosis.  Journal of Neurophysiology 107:448-54. 

Schonewille, M., Gao, Z., Boele, H., Vinueza Veloz, M.F., , Amerika, W.E., Simek, A.A.M., De Jeu, M.T.G., Steinberg, J.P., Takamiya , K., Hoebeek, F.E., Linden, D.J.,  Huganir, R.H. and De Zeeuw, C.I. (2011).  Re-evaluating the role of LTD in cerebellar motor learning. Neuron, 70, 43-50. 

Smith-Hicks, C., Xiao, B., Deng, R., Ji, Y., Shepherd, J.D., Kuhl, D., Huganir, R.L.,  Ginty, D.D., Worley, P.F., Linden, D.J. (2010)..  SRF binding to SRE 6.9 in the Arc promoter is essential for the late phase of cerebellar LTD.   Nature Neuroscience 13;1082-1089

Hu, J.-H., Park, J.M., Park, S., Xiao, B., Dehoff, M.H., Kim, S., Schwarz, M., Huganir, R., Seeburg, P.H., Linden, D.J. and Worley, P.F. (2010)  Homeostatic scaling requires group I mGluR activation mediated by Homer 1a.  Neuron 68, 1128-1142.