Mollie Meffert MD, PhD

Associate Professor of Biological Chemistry

Laurel M. Oldach, Kirill Gorshkov, William T. Mills IV, Jin Zhang*, and *Mollie K. Meffert (2018) A biosensor for MAPK-dependent Lin28 signaling. Molecular Biology of the Cell; 29(10):1157-1167.

Erica C. Dresselhaus, Matthew C. Boersma, Mollie K. Meffert (2018) Targeting of NF-kB to dendritic spines is required for synaptic signaling and spine development. Journal of Neuroscience.; 8(17): 4093-4103.

Erica C. Dresselhaus, Mollie K. Meffert (2019) Cellular specificity of NF-kB function in the nervous system. Special Topic, Frontiers in Immunology; 10: 1-14.

Carlos A. Pardo and Mollie K. Meffert (2018) Animal Models in Autism Research: The Legacy of Paul Patterson. Experimental Neurology v.299, 197 -98.

Alexandra M. Amen, Claudia R. Ruiz, Jay Shi, Megha Subramanian, Daniel L. Pham, and Mollie K. Meffert (2017) A rapid induction mechanism for Lin28a in trophic responses. Molecular Cell, 65 (3); 490 - 503. 

Megha Subramanian, Christina K. Timmerman, Joshua L. Schwartz, Daniel L. Pham, and Mollie K. Meffert (2015), Characterizing Autism Spectrum Disorders by Key Biochemical Pathways. Frontiers in Neuroscience, 9: 313.

Alexandra M. Amen, Daniel L. Pham, and Mollie K. Meffert (2016) Posttranscriptional regulation by Brain-Derived Neurotrophic Factor in the nervous system. In KMJ Menon and A.Aron Goldstrohm (Ed) Post-transcriptional regulation of endocrine function. Springer Press, p315-337.

Anca B. Mihalas and Meffert, M.K. (2015) IKK Kinase Assay for Assessment of Canonical NF-kB Activation in Neurons. Methods in Molecular Biology. v.1280, 61-74.

Claudia R. Ruiz, Jay Shi, and Mollie K. Meffert (2014). Transcript Specificity in BDNF-regulated Protein Synthesis. Neuropharmacology (Special Issue: BDNF regulation of synaptic structure, function, and plasticity), 76; 657-63. 

Anca B. Mihalas, Yoichi Araki, Richard L. Huganir, and Mollie K. Meffert (2013), Opposing action of nuclear factor kB and Polo-like kinases determines a homeostatic endpoint for excitatory synaptic adaptation. J.Neurosci., 16; 16490-501.

Yu-Wen A. Huang*, Claudia R. Ruiz*, E.C.H. Eyler*, Kathie Lin, and Mollie K. Meffert (2012), Dual regulation of miRNA biogenesis generates target specificity in neurotrophin-induced protein synthesis. Cell, 148(5); 933-946. 

Matthew C. Boersma*, Erica C. Dresselhaus*, Lindsay M. De Biase, Anca B. Mihalas, Dwight E. Bergles, and Mollie K. Meffert (2011), A requirement for NF-kB in developmental and plasticity-associated synaptogenesis. J.Neurosci., 31; 5414-5425. 

Cynthia K. Shrum, Daniel Defrancisco, and Mollie K. Meffert. (2009) Stimulated nuclear translocation of NF-kB and shuttling differentially depend on dynein and the dynactin complex. PNAS, 106; 2647-2652. 

Matthew C. Boersma and Mollie K. Meffert (2008) Novel roles for the NF-kB signaling pathway in regulating neuronal function. Science Signaling 1, pe7.

Cynthia K. Shrum and Mollie K. Meffert (2008). The NF- kB Family in Learning and Memory. In J. David Sweatt(Ed.), Molecular Mechanisms of Memory. Vol. [4] of Learning and Memory: A Comprehensive Reference (J.Byrne Editor), pp. [567-586] Oxford: Elsevier

Mark P. Mattson and Mollie K. Meffert (2006). Roles for NF-kB in nerve cell survival, plasticity, and disease. Cell Death and Differentiation 13, 852-60.

Mollie K. Meffert and David Baltimore (2005). Physiological functions for brain NF-kB. Trends in Neurosciences 28, 37-43. 

Mollie K. Meffert, Jolene M. Chang, Brian J. Wiltgen, Michael S. Fanselow, David Baltimore (2003). NF-kB functions in synaptic signaling and behavior. Nature Neuroscience 6, 1072 - 1078. PMID: 12947408

Mollie K. Meffert, Nicole C. Calakos, Richard H. Scheller, Howard Schulman (1996). Nitric oxide modulates synaptic vesicle docking / fusion reactions. Neuron 16, 1229-1236. 

Mollie K. Meffert*, Jane E. Haley*, Erin M. Schuman, Howard Schulman, and Daniel V. Madison (1994). Inhibition of hippocampal heme oxygenase, nitric oxide synthase and long-term potentiation by metalloporphyrins. Neuron 13, 1225-1233. 

Mollie K. Meffert, Brett A. Premack, and Howard Schulman (1994). Nitric oxide stimulates calcium-independent synaptic vesicle release. Neuron 12, 1235-1244.