Pankaj Jay Pasricha MD

Dir., Johns Hopkins Center for Neurogastroenterology, Prof. of Medicine and Neurosciences, Johns Hopkins School of Medicine, Prof. of Innovation Management, Johns Hopkins Carey School of Business




Pasricha PJ, Ravich WJ, Hendrix TR, Sostre S, Jones B, Kalloo AN. Intrasphincteric botulinum toxin injection for the treatment of achalasia. N Engl J Med 1995;332:774-8.

Hoogerwerf WA, Zou L, Shenoy M, Micci MAM, Lee-Hellmich H,  Xiao SY, Winston, JH,  Pasricha PJ. The proteinase-activated receptor 2 is involved in nociception. J Neuroscience 2001;21:9036-42.

Hoogerwerf WA, Shenoy M, Winston JH, Xiao SY, He Z, Pasricha PJ.  Trypsin mediates nociception via the proteinase-activated receptor 2: a potentially novel role in pancreatic pain.  Gastroenterology 2004;127:883-91.

Xu GY, Winston JH, Shenoy MM, Yin H, Pasricha PJ. .Enhanced excitability and suppression of A-type potassium current of pancreas specific afferent neurons in a rat model of chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2006;291:G424-31.

Winston J, Shenoy M, Medley D, Naniwadekar A, Pasricha PJ. The Vanilloid Receptor Initiates and Maintains Colonic Hypersensitivity Induced by Neonatal Colon Irritation in Rats. Gastroenterology 2007 Feb;132(2):615-27.

Xu G, Winston J, Shenoy M, Yin H, Pendyala S, Pasricha PJ. Transient Receptor Potential Vanilloid 1 Mediates Hyperalgesia and Is Upregulated in a Rat Model of Painful Chronic Pancreatitis. Gastroenterology 2007: Jun 20

Xu GY, Shenoy M, Winston JH, Mittal S, Pasricha PJ. P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivity.Gut. 2008 Feb 12; [Epub ahead of print]

Liu LS, Winston JH, Shenoy MM, Song GQ, Chen JD, Pasricha PJ: A rat model of chronic gastric sensorimotor dysfunction resulting from transient neonatal gastric irritation. Gastroenterology 2008, 134(7):2070-2079.

Zhu Y, Colak T, Shenoy M, Liu L, Pai R, Li C, Mehta K, Pasricha PJ. Nerve Growth Factor Modulates TRPV1 Expression and Function and Mediates Pain in Chronic Pancreatitis. Gastroenterology. 2011 Jul;141(1):370-7

Liu L,  Li Q, Sapolsky R, Liao M, Mehta K, Bhargava A, Pasricha PJ. Transient gastric irritation in the neonatal rats leads to changes in hypothalamic CRF expression, depression- and anxiety-like behavior as adults. PLOS One. 2011 PLoS One. 2011 May 12;6(5):e19498.

Kulkarni S, Zou B, Hanson J, Micci MA, Tiwari G, Becker L, Kaiser M, Xie XS, Pasricha PJ. Gut-derived factors promote neurogenesis of CNS-neural stem cells and nudge their differentiation to an enteric-like neuronal phenotype. Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G644-55.

Grover M, Farrugia G, Lurken MS, Bernard CE, Faussone-Pellegrini MS, SmyrkTC, Parkman HP, Abell TL, Snape WJ, Hasler WL, Ünalp-Arida A, Nguyen L, Koch KL, Calles J, Lee L, Tonascia J, Hamilton FA, Pasricha PJ; NIDDK Gastroparesis Clinical Research Consortium. Cellular changes in diabetic and idiopathic gastroparesis. Gastroenterology. 2011 May;140(5):1575-85.

Becker L, Kulkarni S, Tiwari G, Micci MA, Pasricha PJ. Divergent fate and origin of neurosphere-like bodies from different layers of the gut. Am J Physiol Gastrointest Liver Physiol. 2012 Feb 23. [Epub ahead of print]

Grover M, Bernard CE, Pasricha PJ et al Clinical-histological associations in gastroparesis: results from the Gastroparesis Clinical Research Consortium. Neurogastroenterol Motil. 2012 Feb 17. [Epub ahead of print]

Parkman HP, Van Natta ML, Abell TL, McCallum RW, Sarosiek I, Nguyen L, Snape WJ, Koch KL, Hasler WL, Farrugia G, Lee L, Unalp-Arida A, Tonascia J, Hamilton F, Pasricha PJ. Effect of nortriptyline on symptoms of idiopathic gastroparesis: the NORIG randomized clinical trial. JAMA 2013 Dec 25;310(24):2640-9. d10.1001/jama.2013.282833.