Hongjun Song PhD

Professor of Neuroscience

Shin, J., Ming, G-l. and Song, H. (2014). Decoding neuronal transcriptomes and epigenomes via high-throughput sequencing. Nature Neuroscience (In press).

Wen, W., Nguyen, H.N.N., Guo, Z., Lalli, M.A., Wang, X., Su, Y., Kim, N-S., Yoon, K.J., Shin, J., Zhang, C.,  Makri, G., Nauen, D., Yu, H., Guzman, E., Chiang, C-H., Yoritomo, N., Kaibuchi, K., Zou, J., Christian, K.M., Cheng, L., Ross, C.A., Margolis, R.L., Chen, G., Kosik, K.S., Song, H-j., and Ming, G-l. (2014). Synaptic dysregulation in a human iPSC model of major mental disorders. Nature (Epub ahead of print).

Yoon, K.J., Nguyen, H.N., Ursini, G., Zhang, F., Kim, N-S., Wen, Z., Makri, G., Nauen, D., Shin, J.H., Park, Y., Chung, R., Pekle, E., Zhang, C., Towe, M., Hussaini S, M.Q., Lee, Y., Rujescu, D., St. Clair, D., Kleinman, J.E., Hyde, T.M., Krauss, G., Christian, K.M., Rapoport, J.L., Weinberger, D.R., Song, H-j., and Ming, G-l. (2014). Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity. Cell Stem Cell 15, 79-91.

Guo, J.U., Su, Y., Shin, J.H., Shin, J., Li, H., Xie, B., Zhong, C., Hu, S., Le, T., Fan, G., Zhu, H., Chang, Q., Gao, Y., Ming, G.L., Song, H. (2014). Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain. Nature Neuroscience 17, 215-22.

Song, J., Sun, J., Moss, J., Wen, Z., Sun, G.J., Hsu, D., Zhong, C., Davoudi, H., Christian, K.M., Toni, N., Ming, G.L., and Song, H. (2013). Parvalbumin interneurons mediate neuronal circuitry-neurogenesis coupling in the adult hippocampus. Nature Neuroscience 16, 1728-1730.

Jang, M.H., Bonaguidi, M.A., Kitabatake, Y., Sun, J., Song, J., Kang, E., Jun, H., Zhong, C., Su, Y., Guo, J.U., Wang, M.X., Sailor, K.A., Kim, J.Y., Gao, Y., Chiristian, K.M., Ming, G.L., and Song, H. (2013) Secreted frizzled-related protein 3 regulates activity-dependent adult hippocampal neurogenesis.  Cell Stem Cell 12:215-23.

Song, J., Zhong, C., Bonaguidi, M.A., Sun, G.J., Hsu, D., Gu, Y., Meletis, K., Huang, Z.J., Ge, S., Enikolopov, G., Deisseroth, K., Luscher, B., Christian, K.M., Ming, G.L.#, and Song, H.# (2012). Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision. Nature 489:150-4.

Guo, J. U., Ma, D.K., Mo, H., Ball, M.P., Jang, M.H., Bonaguidi, M.A., Balazer, J.A. Eaves, H.L., Xie, B., Ford, E. Zhang, K., Ming, G-l., Gao, Y.#, and Song, H.# (2011). Neuronal activity modifies DNA methylation landscape in the adult brain. Nat. Neurosci. 14:1345-51.

Bonaguidi, M.A., Wheeler, M.A., Shapiro, J.S., Stadel, R.P., Sun, G.J., Ming, G-l.#, and Song, H.# (2011).  In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics. Cell 145, 1142-55.

Ming, G.L. and Song, H. (2011). Adult neurogenesis in the mammalian brain: Significant answers and significant questions. Neuron 70, 687-702.

Guo, J.U., Su, Y., Zhong, C., Ming, G.L., and Song, H. (2011). Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 145:423-34.

Ma, D.K., Marchetto, M.C., Guo, J.U., Ming, G.L., Gage, F.H., and Song H. (2010). Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat Neurosci. 13:1338-44.

Ma, D.K., Jang, M.H., Guo, J.U., Kitabatake, Y., Chang, M.L., Pow-Anpongkul, N., Flavell, R.A., Lu, B., Ming, G.L., Song, H. (2009). Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 323:1074-7.

Duan, X., Chang, J., Ge, S-y., Faulkner, R., Liu, X-b., Kim, J.Y., Yang, C-h., Ma, D., Liu, C., Cheng, H.J., Ming, G-l., Lu, B. and Song, H-j. (2007). Disrupted-In-Schizophrenia 1 regulates integration of new neurons in the adult brain. Cell 13, 1146-58

Ge, S., Goh, E.L., Sailor, K.A., Kitabatake, Y., Ming, G.L.#, Song, H.# (2006). GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature 439:589-93.