Johns Hopkins University, Department of Neuroscience
 

Paul Worley - Recent Papers

 

  • Steward, O., Wallace, C. S., Lyford, G. L., and Worley, P. F. (1998). Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites. Neuron 21, 741-751. [PDF]

 

  • Tu, J. C., Xiao, B., Yuan, J. P., Lanahan, A. A., Leoffert, K., Li, M., Linden, D. J., and Worley, P. F. (1998). Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors. Neuron 21, 717-726. [PDF]
  • Guzowski, J. F., McNaughton, B. L., Barnes, C. A., and Worley, P. F. (1999). Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles. Nat Neurosci 2, 1120-1124. [PDF]
  • Xu, D., Hopf, C., Reddy, R., Cho, R. W., Guo, L., Lanahan, A., Petralia, R. S., Wenthold, R. J., O'Brien, R. J., and Worley, P. (2003). Narp and NP1 form heterocomplexes that function in developmental and activity-dependent synaptic plasticity. Neuron 39, 513-528. [PDF]

 

  • Yuan, J. P., Kiselyov, K., Shin, D. M., Chen, J., Shcheynikov, N., Kang, S. H., Dehoff, M. H., Schwarz, M. K., Seeburg, P. H., Muallem, S., and Worley, P. F. (2003). Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell 114, 777-789. [PDF]
  • Kim, S.J., Kim, Yu Shin, Yuan, J., Petralia, R.S., Worley, P.F., and Linden, D. (2003). Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1. Nature Vol. 426(6964): 285-291. [PDF]


  • Chowdhury S., Shepherd J., Okuno, H., Lyford G., Petralia R., Plath N., Kuhl D., Huganir R.L.,  and Worley, P.F.  (2006)  Arc/Arg3.1 Interacts with the Endocytic Machinery to Regulate AMPA Receptor Trafficking.  Neuron, Vol. 52(3):  445-459.  [PDF]
  • Shepherd, J., Rumbaugh, G., Wu, J., Chowdhury, S., Plath, N., Kuhl, D., Huganir, R.L., and Worley, P.F.  (2006)  Arc/Arg3.1 Mediates Homeostatic Synaptic Scaling of AMPA Receptors.  Neuron, Vol. 52(3): 475-484.  [PDF]
  • Huang, G., Zeng, W., Kim, J.Y., Yuan, J.P., Han, LinHuang, H., Muallem, S., and Worley, P.F.  (2006)  STIML carboxyl-terminus activates native SOC, /crac and TRPC1 channels.  Nature Cell Biology, Vol. 8(9):  1003-1010.   [PDF]
  • Cho, R.W., Park, J.M., Wolff, S.B.E., Xu, D., Hopf, C., Kim, J.-A., Reddy, R.C., Petralia, R.S., Perin, M.S., Linden, D.J., Worley, P.F. (2008)  mGluR1/5-dependent Long-Term Depression requires the regulated ectodomain cleavage of neuronal pentraxin NPR by TACE. Neuron Vol. 57(6), 858-871.
  • Park, S., Park, J.M., Kim, S., Kim, J.-A., Ryazanov, A.G., Linden, D.J., and Worley, P.F. (2008)  Eukaryotic Elongation Factor 2 (eEF2) and Fragile X Mental Retardation Protein (FMRP) Control the Dynamic Translation of Arc Essential for mGluR-dependent Synaptic Depression. (in review Neuron).

 

 

 

 

 

 
© 2005 Department of Neuroscience, Johns Hopkins University School of Medicine