Neural Circuits, Ensembles + Connectomes

The functioning of neural circuits involves millions of neurons with the ability to combine and coordinate in myriad ways to form ensembles. Human connectome research, in which Hopkins plays a major role, is expected to map these complex interactions


Early studies in brain science, including breakthroughs from pioneering Johns Hopkins researcher and professor Dr. Vernon Mountcastle, were designed to disentangle the network complexity of the brain by exploiting the relative accessibility of sensory receptive fields. Pioneering work at Hopkins on these sensory fields would reveal network principles such as the columnar organization of the cerebral cortex.

More recently, the advent of modern molecular, viral, and optogenetic approaches has allowed neuroscientists to discover new principles of ensemble organization. Experimental tools used widely in the department include in vivo and ex vivo electrophysiology; calcium imaging; anatomical mapping; molecular targeting of synapses and circuits with viral and optogenetic strategies; as well as behavioral analysis to determine the functional properties of identified circuits. These tools are being used to dissect neural circuits controlling reward and motivation, social interactions, complex movements, and cognition, as well as sensory perception.

 

  • Yeka Aponte, PhD Position: Adjunct Assistant Professor Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Neurobiology of Disease
  • Amy Bastian, PhD Position: Professor of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Neurobiology of Disease
  • Mary Blue, PhD Position: Associate Professor of Neurology Areas of research: Developmental Neuroscience, Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience, Neurobiology of Disease
  • Antonello Bonci, MD Position: Adjunct Professor in Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience
  • Solange Brown, MD, PhD Position: Assistant Professor of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience, Neurobiology of Disease
  • Pablo Celnik, MD Position: Associate Professor of Physical Medicine and Rehabilitation, Neurology and Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Neurobiology of Disease
  • Jeremiah Cohen, PhD Position: Assistant Professor of Neuroscience Brain Science Institute Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience
  • Ed Connor, PhD Position: Professor of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Susan Courtney-Faruqee, PhD Position: Professor of Psychological and Brain Sciences Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Neurobiology of Disease
  • John Desmond, PhD Position: Professor of Neurology Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Gul Dolen, MD, PhD Position: Assistant Professor of Neuroscience, Brain Science Institute, Wendy Klag Center, Director of Diversity Areas of research: Developmental Neuroscience, Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience, Neurobiology of Disease
  • Michela Gallagher, PhD Position: Krieger-Eisenhower Professor of Psychological and Brain Sciences and Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience, Neurobiology of Disease
  • Roland Griffiths, PhD Position: Professor of Behavioral Biology Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Neurobiology of Disease
  • Stewart Hendry, PhD Position: Professor of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience
  • Peter Holland, PhD Position: Krieger-Eisenhower Professor of Psychological and Brain Sciences Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Patricia Janak, PhD Position: Bloomberg Distinguished Professor of Neuroscience and Psychological and Brain Sciences Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Neurobiology of Disease
  • Alfredo Kirkwood, PhD Position: Professor of Neuroscience Areas of research: Developmental Neuroscience, Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience
  • James Knierim, PhD Position: Professor of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • John Krakauer, MA, MD Position: Professor of Neurology and Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Hey-Kyoung Lee, PhD Position: Professor of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience
  • David Linden, PhD Position: Professor of Neuroscience Areas of research: Cellular + Molecular Neuroscience, Neural Circuits, Ensembles + Connectomes, Neurobiology of Disease
  • Brady Maher, PhD Position: Assistant Professor of Psychiatry and Behavior Sciences Areas of research: Developmental Neuroscience, Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience, Neurobiology of Disease
  • Keri Martinowich, PhD Position: Lead Investigator, Lieber Institute for Brain Development Assistant Professor, Department of Psychiatry Assistant Professor, Department of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Neurobiology of Disease
  • Conor McMeniman, PhD Position: Assistant Professor of Molecular Microbiology & Immunology Areas of research: Cellular + Molecular Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Mollie Meffert, MD, PhD Position: Associate Professor of Biological Chemistry Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience, Neurobiology of Disease
  • Cynthia Moss, PhD Position: Professor of Psychological and Brain Sciences Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Ulrich Mueller, PhD Position: Bloomberg Distinguished Professor of Neuroscience and Biology Areas of research: Neural Circuits, Ensembles + Connectomes, Developmental Neuroscience, Cellular + Molecular Neuroscience, Neurobiology of Disease
  • Jeff Mumm, PhD Position: Associate Professor of Ocular Molecular Biology Areas of research: Neural Circuits, Ensembles + Connectomes, Developmental Neuroscience, Cellular + Molecular Neuroscience, Neurobiology of Disease
  • Shreesh Mysore, PhD Position: Assistant Professor of Psychological and Brain Sciences Areas of research: Neural Circuits, Ensembles + Connectomes, Systems, Cognitive + Computational Neuroscience
  • Ernst Niebur, PhD Position: Professor of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Kristina Nielsen, PhD Position: Assistant Professor of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Daniel O'Connor, PhD Position: Assistant Professor of Neuroscience Brain Science Institute Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience
  • Mikhail Pletnikov, MD, PhD Position: Professor of Psychiatry, Neuroscience, and Molecular and Comparative Pathobiology Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Neurobiology of Disease
  • Christopher Potter, PhD Position: Assistant Professor of Neuroscience Center for Sensory Biology Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience
  • Irving Reti, MBBS Position: Associate Professor of Psychiatry and Behavioral Sciences Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Geoffrey Schoenbaum, MD, PhD Position: Branch Chief and Senior Investigator, Tenured Cellular Neurobiology Research Branch Behavioral Neurophysiology Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Lawrence Schramm, PHD Position: Professor of Biomedical Engineering and Neuroscience Areas of research: Neural Circuits, Ensembles + Connectomes, Systems, Cognitive + Computational Neuroscience, Neurobiology of Disease
  • Reza Shadmehr, PhD Position: Professor of Biomedical Engineering and Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Neurobiology of Disease
  • Marshall Hussain Shuler, PhD Position: Associate Professor of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Hongjun Song, PhD Position: Professor of Neuroscience Areas of research: Developmental Neuroscience, Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience, Neurobiology of Disease
  • Veit Stuphorn, PhD Position: Associate Professor of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Joshua Vogelstein, PhD Position: Assistant Professor of Biomedical Engineering Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Rudiger von der Heydt, PhD Position: Professor Emeritus of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • Paul Worley, MD Position: Professor of Neuroscience Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience
  • Mark Wu, MD, PhD Position: Associate Professor of Neurology Areas of research: Neural Circuits, Ensembles + Connectomes, Cellular + Molecular Neuroscience, Neurobiology of Disease
  • Eric Young, PhD Position: Professor Emeritus of Biomedical Engineering Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes
  • David Zee, MD Position: Professor of Neurology Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes, Neurobiology of Disease
  • Kechen Zhang, PhD Position: Assistant Professor of Biomedical Engineering Areas of research: Systems, Cognitive + Computational Neuroscience, Neural Circuits, Ensembles + Connectomes