Johns Hopkins School of Medicine

Jung K, Kruessel S, Yoo S, An M, Burke B, Schappaugh N, Choi Y, Gu Z, Blackshaw S, Costa RM, Kwon HB. Dopamine-mediated formation of a memory module for goal-directed navigation in the nucleus accumbens. 2024; Nature Neuroscience (In press).

Lin W, Phatarphekar A, Zhong Y, Liu L, Kwon HB, Gerwick WH, Wang Y, Mehta S, Zhang J. A Light-gated Integrator for Highlighting Kinase Activity in Living Cells. 2024; Nature Communications (In press)

Krüssel S, Deb I, Son S, Ewall G, Chang M, Lee H-K, Heo WD, Kwon HB. Exuberant de novo dendritic spine growth in mature neurons.; iScience 2024 Jul 18;27(8):110535. doi: 10.1016/j.isci.2024.110535. eCollection 2024 Aug 16.

Son S, Nagahama K, Lee J, Jung K, Kwak C, Kim J, Noh YW, Kim E, Lee S^#, Kwon HB^#, Heo WD^#. Real-time visualization of structural dynamics of synapses in live cells in vivo; Nature Methods 2024 Jan 8. doi: 10.1038/s41592-023-02122-4). ^#Corresponding authors

Cui M, Lee S, Ban SH, Kim JY, Choi SK, Han J, Kim Y, Han K, Lee D, Kwon HB, Lee D. LAUNCHER: A single-component, light-assisted uncaging switch for endoproteolytic release. 2023; Nature Chemical Biology 2023 Nov 16. doi: 10.1038/s41589-023-01480-6.

Jung K, Chang M, Steinecke A, Burke B, Choi Y, Oisi Y, Fitzpatrick D, Taniguchi H, Kwon HB. An adaptive behavioral control motif mediated by cortical axo-axonic inhibition. Nature Neuroscience. 2023 Aug; 26(8):1379-1393. doi: 10.1038/s41593-023-01380-x. Epub 2023 Jul 20.

Valtcheva S, Issa HA, Bair-Marshall CJ, Martin KA, Jung K, Zhang Y, Kwon HB, Froemke RC. Neural circuitry for maternal oxytocin release induced by infant cries. 2023; Nature 2023 Sep;6 21(7980):788-795. doi: 10.1038/s41586-023-06540-4. Epub 2023 Sep 20.

Kwon HB. Writing and reading cellular histories. Nature Biotechnology 2023; Jan 2. doi: 10.1038/s41587-022-01597-

Hyun JH, Nagahama K, Namkung H, Mignocchi N, Hannan P, Kruessel S, Kwak C, McElroy A, Liu B, Cui M, Lee S, Lee D, Huganir RL, Sawa A, Kwon HB. Tagging active neurons by soma-targeted Cal-Light. Nature Communications 2022; Dec 12; 13(1):7692 

Chang M, Lee OC, Bu G, Oh J, Yunn NO, Ryu SH, Kwon HB, Kolomeisky AB, Shim SH, Doh J, Jeon JH, Lee JB. Formation of cellular closed-ended tunneling nanotubes through mechanical deformation. Science Advances 2022; Apr;8(13):eabj3995. doi: 10.1126/sciadv.abj3995. Epub 2022 Mar 30.

Jung K, Choi D, Kwon HB. Cortical control of chandelier cells in neural codes. Frontiers in Cellular Neuroscience. 2022; Oct 10;16:99248. doi: 10.3389/fncel.2022.992409. eCollection 2022

Lee D and Kwon HB. Current and future techniques for detecting oxytocin: Focusing on genetically-encoded GPCR sensors. Journal of Neuroscience Methods 2021; Nov 8;366:109407.

Hayano Y, Ishino Y, Hyun JH, Orozco CG, Steinecke A, Potts E, Oisi Y, Thomas CI, Guerrero-Given D, Kim E, Kwon HB, Kamasawa N, Taniguchi H. IgSF11 homophilic adhesion proteins promote layer-specific synaptic assembly of the cortical interneuron subtype. Science Advances 2021; Jul 14;7(29):eabf1600. doi: 10.1126/sciadv.abf1600. Print 2021 Jul.

Lituma PJ, Kwon HB, Alvina K, Lujan R, Castillo PE. Presynaptic NMDA receptors facilitate short-term plasticity and BDNF release at hippocampal mossy fiber synapses. eLife 2021; Jun 1;10:e66612. doi: 10.7554/eLife.66612

Zheng HJV, Meagher JP, Xu D, Patal YA, O’Connor DH, Kwon HB. Environmental enrichment sharpens sensory acuity by enhancing information coding in barrel cortex and premotor cortex. ENEURO 2021; DOI: https://doi.org/10.1523/ENEURO.0309-20.2021 (PubMed PMID: 33893166)

Oh WC, Rodríguez G, Asede D, Jung K, Hwang IW, Ogelman R, Bolton MM, Kwon HB. Dysregulation of Mesoprefrontal Dopamine Circuit Mediates Early Life Stress-Induced Excitatory/Inhibitory Synaptic Imbalance in the Prefrontal Cortex. Cell Reports 2021; May 4;35(5):109074. (PubMed PMID: 33951422).

Mignocchi N, Kruessel S, Jung K, Lee D, Kwon HB. Development of a genetically-encoded oxytocin sensor. doi: https://doi.org/10.1101/2020.07.14.202598; 2020, BioRxiv 

Yetman MJ, Washburn E, Hyun JH, Osakada F, Hayano Y, Zeng H, Callaway EM, Kwon HB, Taniguchi H. Intersectional monosynaptic tracing for dissecting subtype-specific organization of GABAergic interneuron inputs. Nature Neuroscience. 2019; 22 (3): 492-502

Kim J*, Lee S*, Jung K*, Oh WC, Kim N, Son S, Jo Y, Kwon HB^#, Heo WD^#. Intensiometric biosensors visualize multiple small GTPases activities in vivo. Nature Communications. 2019; Jan 14; 10(1):211 * equal contribution ^#Corresponding authors 

Beas-Alvarez BS, Wright BJ, Skirzewwski M, Leng Y, Hyun JH, Koita O, Ringelberg N, Kwon HB, Buonanno A, and Penzo MA. The locus coeruleus drives disinhibition in the midline thalamus via dopaminergic mechanism. Nature Neuroscience. 2018; 21(7): 963~973

Lee D*, Hyun JH*, Jung K, Hannan P, Kwon HB. A calcium- and light-gated switch to induce gene expression in activated neurons. Nature Biotechnology. 2017; 35(9): 858-863 *equal contribution * Highlighted in Nature Methods * Highlighted in Nature Chemical Biology * News and Views in Nature Biotechnology

Lee D*, Creed M*, Jung K*, Stefanelli T, Wendler DJ, Oh WC, Mignocchi NL, Luscher C, Kwon HB. Temporally precise labeling and control of neuromodulatory circuits in mammalian brain. Nature Methods. 2017; 14(5): 495-503 *equal contribution

Sigler A*, Oh WC*, Imig C*, Altas B, Kawabe H, Cooper BH, Kwon HB, Rhee JS, Brose N. Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release. Neuron. 2017; 94(2):304-311 *equal contribution

Oh WC, Lutzu S, Castillo PE and Kwon HB. De novo synaptogenesis induced by GABA in the developing mouse cortex. Science. 2016; 353(6303): 1037-1040 * Highlighted in Nature Review Neuroscience

Kim T*, Oh WC*, Choi JH and Kwon HB. Emergence of functional subnetwork in layer 2/3 cortex induced by sequential spikes in vivo. Proc Natl Acad Sci U S A. 2016; Mar 8; 113(10): E1372-81 *equal contribution

Kwon HB, Kozorovitskiy Y, Oh WJ, Akhtar N, Saulnier JL, Gu C, Sabatini BL. Neuroligin-1-dependent intercellular competition regulates cortical synaptogenesis and synapse number. Nature Neuroscience. 2012; 15(12):1667~1674

Kwon HB and Sabatini BL. Glutamate induces de novo growth of functional spines in developing cortex. Nature. 2011; 474 (7349):100-104

Kwon HB and Castillo PE. Role of Glutamate Autoreceptors at Hippocampal Mossy Fiber Synapses. Neuron. 2008; 60: 1082-1094

Kwon HB and Castillo PE. Long-Term Potentiation Selectively Expressed by NMDA Receptors at Hippocampal Mossy Fiber Synapses. Neuron. 2008; 57: 108-20

Kwon HB, Kim SH, Kim SE, Jang IH, Ahn Y, Lee WJ, Choi KY. Drosophila Extracellular Signal Regulated Kinase Involves in The Insulin Mediated Proliferation of Schneider Cells. J. Biol. Chem. 2002; 277: 14853-14858