Seth Margolis PhD

Associate Professor of Biological Chemistry




  1. Villalón Landeros, E., Kho, S.C., Church, T.R., Brennan, A., Türker, F., Delannoy, M., Caterina, M.J., and Margolis, S.S. (2024). The nociceptive activity of peripheral sensory neurons is modulated by the neuronal membrane proteasome. Cell Rep 43, 114058. 10.1016/j.celrep.2024.114058.
  2. Turker, F., Brennan, A. & Margolis, S. S. (2024) Neuronal membrane proteasome-derived peptides modulate NMDAR-dependent neuronal signaling to promote changes in gene expression. Mol Biol Cell 35, ar6. 10.1091/mbc.E23-06-0218
  3. Ramachandran, K. V., Fu, J. M., Schaffer, T. B., Na, C. H., Delannoy, M. & Margolis, S. S. (2018) Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome. Mol Cell 71, 169-177 e166. 10.1016/j.molcel.2018.06.013
  4. Ramachandran, K. V. & Margolis, S. S. (2017) A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal function. Nat Struct Mol Biol 24, 419-430. 10.1038/nsmb.3389