Jeff Mumm PhD

Helen Larson & Charles Glenn Grover Professor in Ophthalmology, Wilmer Eye Institute Associate Professor in Ophthalmology




White D, Sengupta S, Saxena MT, Xu Q, Hanes J, Ding D, Ji H, Mumm J. Immunomodulation-accelerated neuronal regeneration following selective rod photoreceptor cell ablation in the zebrafish retina. Proceedings of the National Academy of Sciences USA, 2017; 114, E3719–E3728.

Vergara N, Flores-Bellver M, Aparicio-Domingo S, McNally M, Saxena M, Mumm J and Canto-Soler V. Three-dimensional automated reporter quantification (3D-ARQ) technology enables quantitative screening in retinal organoids. Development, 2017, 144(20):3698-3705.
White D*, Eroglu A*, Wang G*, Zhang L, Sengupta S, Ding D, Rajpurohit S, Walker S, Ji H, Qian J, Mumm, J. ARQiv-HTS, a versatile whole-organism screening platform enabling in vivo drug discovery at high-throughput rates. Nature Protocol, 2016, 11: 2432–2453. *equal contribution

Wang G, Rajpurohit S, Delaspre F, Walker F, White D, Ceasrine A, Kuruvilla R, Li R, Shim J, Liu J, Parsons M, Mumm J. First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass. eLife 2015;10.7554/eLife.08261.

Mathias J, Zhang Z, Saxena M, Mumm J. Enhanced cell-specific ablation in zebrafish using a triple mutant of E. coli nitroreductase. Zebrafish. 2014, 11: 85-97.

Sengupta S, Zhang L, Mumm J. Chemical genetics & regeneration. Future Medicinal Chemistry – Special Issue, Chemical Biology. 2015; 16: 2263-83.

Wang K, Milkie D, Saxena A, Engerer P, Misgeld T, Bronner M, Mumm J, Betzig E. Rapid adaptive optical recovery of optimal resolution over large multicellular volumes. Nature Methods. 2014, 11: 625–628.

Walker S*, Ariga J*, Mathias J, Coothankandaswamy V, Xie X, Distel M, Koster R, Parsons M, Bhalla K, Saxena M, Mumm J. Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish. PLoS ONE. 2012; 7:e29916

Ariga J, Walker S, Mumm J. Multicolor time-lapse imaging of transgenic zebrafish: visualizing retinal stem cells activated by targeted neuronal cell ablation. Journal of Visualized Experiments. 2010; Sep 20;(43).