Taeyoung Hwang PhD

Investigator, Lieber Institute for Brain Development; Assistant Professor of Neurology and Neuroscience

taeyoung.hwang@jhu.edu
Telephone Number: 410-955-1000

855 North Wolfe Street
Suite 300, 3rd Floor
Baltimore, MD 21205
Office: Rangos, Rm 393

Areas of Research
Cellular + Molecular Neuroscience
Developmental Neuroscience
Neurobiology of Disease

Graduate Program Affiliations

Neuroscience Training Program

Understanding the regulatory roles of RNAs in neurons and human brain development

RNA is typically understood as an intermediary molecule between DNA and protein. But, some noncoding RNAs, as well as the noncoding regions of messenger RNA, have been well appreciated as important regulators of gene expression and cellular functions. As increasing numbers of noncoding RNAs are implicated in development and diseases, the forefront of current RNA research centers on understanding its regulatory roles beyond coding potential. My laboratory investigates the roles of regulatory RNAs in the nervous system and aims to understand the RNA-based mechanisms in neural development and brain disorders. We develop computational methods and genomic assays to map regulatory RNAs in the human genome and apply high-throughput tools to evaluate the effects of risk variations on RNA-mediated regulatory mechanisms. Current research projects include characterizing small RNA expression in human brain development, identifying RNA elements driving RNA’s subcellular localization in neurons, and evaluating psychiatric risk variations on RNA-protein interaction dysregulation.


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