Frederick S. Barrett PhD

Associate Professor of Psychiatry and Behavioral Sciences, Neuroscience and Psychological and Brain Sciences; Associate Director, Center for Psychedelic and Consciousness Research




Selected References

Barrett FS, Johnson MW ,& Griffiths RR (2015). Validation of the Revised Mystical Experience Questionnaire in Experimental Sessions with Psilocybin. J of Psychopharm, 29(11), 1182-90.

Barrett FS, Bradstreet MP, Leoutsakos JMS, Johnson MW, Griffiths RR (2016). The Challenging Experience Questionnaire: Characterization of challenging experiences with psilocybin mushrooms. J of Psychopharm, 30(12), 1279-1295.

Barrett FS, & Janata P (2016b). Neural responses to nostalgia-evoking music modeled by elements of dynamic musical structure and individual differences in affective traits. Neuropsychologia, 91, 234–246.

Barrett FS, Carbonaro TM, Hurwitz E, Johnson MW, & Griffiths RR (2017). Double-blind comparison of the two hallucinogens psilocybin and dextromethorphan: effects on cognition. Psychopharmacology, 235(10), 2915-2927.

Barrett FS, Preller KH, & Kaelen M (2018). Psychedelics and music: neuroscience and therapeutic implications. International Review of Psychiatry, 30(4), 350-362.

Barrett FS, Preller KH, Herdener M, Janata P, & Vollenweider FX (2018). Serotonin 2A Receptor Signaling Underlies LSD-induced Alteration of the Neural Response to Dynamic Changes in Music. Cerebral Cortex, 1–12. https://doi.org/10.1093/cercor/bhx257

Barrett FS, Krimmel SR, Griffiths RR, Seminowicz DA, Mathur BN (2020a). Psilocybin acutely alters the functional connectivity of the claustrum with brain networks that support perception, memory, and attention. NeuroImage, 218:116980.

Barrett FS, Doss MK, Sepeda ND, Pekar JJ, & Griffiths RR (2020b). Emotions and brain function are altered up to one month after a single high dose of psilocybin. Scientific Reports.

Barrett FS, Zhou Y, Carbonaro TM, Roberts JM, Smith GS, Griffiths RR, & Wong DF (2022). Human cortical serotonin 2A receptor occupancy by psilocybin measured using [11C] MDL 100,907 dynamic PET and a resting-state fMRI-based brain parcellation. Frontiers in Neuroergonomics, 45.

Collins T, Tillmann B, Barrett FS, Delbé C, Janata P (2014). A combined model of sensory and cognitive representations underlying tonal expectations in music: From audio signals to behavior. Psychological Review, 121(1), 33.

Davis AK, Barrett FS, & Griffiths RR (2020). Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety. Journal of Contextual Behavioral Science15, 39–45. https://doi.org/10.1016/j.jcbs.2019.11.004

Davis AK, Barrett FS, May DG, Cosimano MP, Sepeda ND, Johnson MW, Finan PH, Griffiths RR (2020). Effects of psilocybin-assisted therapy for major depressive disorder: A randomized clinical trial. JAMA Psychiatry

Doss MK, May DG, Johnson MW, Clifton JM, Hedrick SL, Prisinzano TE, Griffiths RR, Barrett FS (2020). The acute effects of the atypical dissociative hallucinogen salvinorin A on functional connectivity in the human brain. Scientific Reports, 10(1), 1-12.

Doss MK, Pova┼żan M, Rosenberg MD, Sepeda ND, Davis AK, Finan PH, Smith GS, Pekar JJ, Barker PB, Griffiths RR & Barrett FS (2021). Psilocybin therapy increases cognitive and neural flexibility in patients with major depressive disorder. Translational Psychiatry11(1), 1–10

Doss MK, Madden MB, Gaddis A, Nebel MB, Griffiths RR, Mathur BN, & Barrett FS (2022). Models of psychedelic drug action: Modulation of cortical-subcortical circuits. Brain: A Journal of Neurology, 145(2):441-456.

Gaddis A, Lidstone DE, Nebel MB, Griffiths RR, Mostofsky SH, Mejia AF, Barrett FS (2022). Psilocybin induces spatially constrained alterations in thalamic functional organization and connectivity. NeuroImage, 260:119434.

Golden TL, Magsamen S, Sandu CC, Roebuck GM, Shi KM, Barrett FS (2022). Effects of setting on psychedelic experiences, therapies, and outcomes: A rapid scoping review of the literature. Disruptive Psychopharmacology, Current Topics in Behavioral Neuroscience, pp 35-70. Springer Verlag.

Madden MB, Stewart BW, White MG, Krimmel SR, Qadir H, Barrett FS, Seminowicz DA, Mathur BN (2022). A role for the claustrum in cognitive control. Trends in Cognitive Sciences, 26(12):1133-1152.

Nikolaidis A, Lancelotta R, Gukasyan N, Griffiths RR, Barrett FS, Davis AK (2023). Subtypes of the psychedelic experience have reproducible and predictable effects on depression and anxiety symptoms. Journal of Affective Disorders, 324, 239-249.

Sayal─▒ C & Barrett FS (2023). The costs and benefits of psychedelics on cognition and mood. Neuron, 111(5), 614-630.