Johns Hopkins School of Medicine

Gamache, T.R., Araki, Y., Huganir, R.L. (2020)  Twenty Years of SynGAP Research: From Synapses to Cognition. J Neurosci. 2020 Feb 19;40(8):1596-1605.

Tan, H.L., Roth, R.H., Graves, A.R., Cudmore, R.H., Huganir, R.L. (2020)  Lamina-specific AMPA receptor dynamics following visual deprivation in vivo. eLife. 2020 Mar 3;9. pii: e52420.   PMCID:  PMC7053996. 

Roth, R., Cudmore, R., Tan, H., Hong, I., Zhang, Y., Huganir, R. (2019) Cortical Synaptic AMPA Receptor Plasticity During Motor Learning. Neuron. 105(5):895-908.  PMCID:  PMC7060107.

Diering, G.H., Huganir, R.L.  (2018) The AMPA Receptor Code of Synaptic Plasticity. Neuron. 100(2):  314-329.

Diering, G.H., Nirujogi, R.S., Roth, R.H., Worley, P.F., Pandey, A., Huganir, R.L. (2017)   Homer1a drives Homeostatic Scaling-down of Excitatory Synapses During Sleep. Science. 355(6324):511-515. PMCID:  PMC5382711.

Roth, R.H., Zhang, Y., Huganir, R.L. (2017) Dynamic imaging of AMPA receptor trafficking in vitro and in vivo. Curr Opin Neurobiol. Apr 12; 45: 51-58. 

Heo, S., Diering, G.H., Na, C.H., Nirujogi, R.S., Bachman, J.L., Pandey, A., Huganir, R.L. (2018) Identification of long-lived synaptic proteins by proteomic analysis of synaptosome protein turnover. Proc Natl Acad Sci USA. 115(16): E3827-E3836. 

Chiu, S.L., Diering, G.H., Ye, B., Takamiya, K., Chen, C-M., Jiang, Y., Niranjan, T., Schwartz, C., Wang, T., Huganir, R.L. (2017) GRASP1 regulates synaptic plasticity and learning through endosomal recycling of AMPA receptors. Neuron. 93(6):  1405-1419. 

Lagerlöf, O., Slocomb, J.E., Hong, I., Aponte, Y., Blackshaw, S., Hart, G.W., Huganir, R.L. (2016) The nutrient sensor OGT in PVN neurons regulates feeding. Science. 351(6279): 1293-6.

Widagdo, J., Chai, Y.J., Ridder, M.C., Chau, Y.Q., Johnson, R.C., Sah, P., Huganir, R.L., Anggono, V. (2015) Activity-Dependent Ubiquitination of GluA1 and GluA2 Regulates AMPA Receptor Intracellular Sorting and Degradation.  Cell Reports. Pii:S2211-1247(15)000028-5.

Zhang, Y., Cudmore, R., Lin, D-T., Linden, D., Huganir, R.L. (2015)  Visualization of NMDA Receptor-Dependent AMPA Receptor Synaptic Plasticity In Vivo. Nature Neuroscience. 18(3): 402-7.

Araki, Y., Zeng, M., Zhang, M., Huganir, R.L.  (2014) Rapid Exclusion of SynGAP from Synaptic Spines Triggers AMPA Receptor Insertion and Spine Enlargement During LTP. Neuron.  85(1): 173-189.

Diering, G., Gustina, A., Huganir, R.L. (2014)  PKA-GluA1 coupling via AKAP5 controls AMPA receptor phosphorylation and cell-surface targeting during bidirectional homeostatic plasticity.  Neuron.  84(4): 790-805.

Sia, G.M., Clem, R. L., Huganir, R.L.  (2013) The human language-associated gene SRPX2 regulates synapse formation and vocalization in mice.  Science.  342(6161): 987-91.

Volk, L.J., Bachman, J.L., Johnson, R., Yu, Y., Huganir, R.L. (2013) PKM-Z is not required for hippocampal synaptic plasticity, learning and memory.  Nature. 493(7432): 420-3. 

Thomas, G.M., Hayashi, T., Chiu, S.L., Chen, C.M., Huganir, R.L. (2012) Palmitoylation by DHHC5/8 targets GRIP1 to dendritic endosomes to regulate AMPA-R trafficking. Neuron. 73(3):482-96.

Makuch, L., Volk, L., Anggono, V., Johnson, R.C., Yu, Y., Duning, K., Kremerskothen, J., Xia, J., Takamiya, K., Huganir, R.L. (2011) Regulation of AMPA receptor function by the human memory-associated gene KIBRA. Neuron. 71(6):1022-9.

Makino, Y., Johnson, R.C., Yu, Y., Takamiya, K., Huganir, R.L. (2011)  Enhanced synaptic plasticity in mice with phosphomimetic mutation of the GluA1 AMPA receptor. Proc Natl Acad Sci U S A. 108(20):8450-5.

Mejias, R., Adamczyk, A., Anggono, V., Niranjan, T., Thomas, G.M., Sharma, K., Skinner, C., Schwartz, C.E., Stevenson, R.E., Fallin, M.D., Kaufmann, W., Pletnikov, M., Valle, D., Huganir, R.L., Wang, T.  (2011) Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 recycling and surface distribution in patients with autism. Proc Natl Acad Sci USA. 108(12):4920-5.  

Clem, R., Huganir, R.L. (2010) Calcium-permeable AMPA receptor dynamics mediate fear memory erasure.  Science.  330(6007): 1108-12. 

Hayashi, T., Thomas, G., Huganir, R.L. (2009) Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking. Neuron. 64(2): 213-226.

Lin, D.T., Makino, Y., Sharma, K., Hayashi, T., Neve, R., Takamiya, K., Huganir, R.L. (2009) Regulation of AMPA receptor GluR1 subunit extrasynaptic insertion events by 4.1N, phosphorylation and palmitoylation. Nat. Neurosci. 12(7): 879-87.

Sia, G.-M., Beique, J.-C., Rumbaugh, G., Cho, R., Worley, P.F., Huganir, R.L. (2007) Interaction of the N-terminal domain of the AMPA receptor GluR4 subunit with the neuronal pentraxin NP1 mediates GluR4 synaptic recruitment. Neuron. 55(1): 87-102.

Steinberg, J.P., Takamiya, K., Shen, Y., Xia, J., Rubio, M.E., Yu, S., Jin, W., Thomas, G.M., Linden, D.J., Huganir, R.L.  (2006) Targeted in vivo mutations of the AMPA receptor subunit GluR2 and its interacting protein PICK1 eliminate cerebellar long-term depression. Neuron. 49(6): 845-60.

Chung, H.J., Steinberg, J.P., Huganir, R.L. and Linden, D.J. (2003) Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression. Science 300:1751-1755.

Lee, H.-K., Takamiya, K., Han, J.-S., Man, H., Kim, C.-H., Rumbaugh, G., Yu, S., Ding, L., He, C., Petralia, R.S., Wenthold, R.J., Gallagher, M., and Huganir, R.L. (2003) Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory. Cell. 112:631-642.

Lee, H.-K., Barbarosie, M., Kameyama, K., Bear, M.F., and Huganir, R.L. (2000) Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity. Nature. 405:955-959.

Ehlers, M.D., Zhang, S., Bernhardt, J.P., and Huganir R.L. (1996) Inactivation of NMDA receptors by direct interaction of calmodulin with NR1 subunit. Cell 84:745-755.

Complete list of published works in MyBibliography: 

http://www.ncbi.nlm.nih.gov/pubmed/?term=Huganir+R.