Johns Hopkins School of Medicine

For a more complete list of publications, click here.

Crerar H#, Scott-Solomon E#, Bodkin-Clarke C#, Andreassi C, Hazbon M, Logie E, Cano-Jaimez M, Gaspari M, Kuruvilla R*, Riccio A*. Regulation of NGF Signaling by an Axonal Untranslated mRNA. Neuron. 2019 Feb 27. pii: S0896-6273(19)30120-5. #co-first authors, *co-corresponding authors.

Ceasrine AM, Lin EE, Lumelsky DN, Iyer R, and Kuruvilla R. Adrb2 controls glucose homeostasis by developmental regulation of pancreatic islet vasculature. Elife. 2018 Oct 10;7. pii: e39689.

Yamashita N, Joshi R, Zhang S, Zhang ZY, Kuruvilla R. Phospho-regulation of soma-to-axon transcytosis of neurotrophin receptors. Dev Cell. 2017 Sep 25;42(6):626-639

Chen CM, Orefice LL, Chiu SL, LeGates TA, Hattar S, Huganir RL, Zhao H, Xu B, Kuruvilla R. Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E619-E628.

Houtz J, Borden P, Ceasrine A, Minichiello L, and Kuruvilla R. Neurotrophin signaling is required for glucose-induced insulin secretion. Dev Cell. 2016 Nov 7;39(3):329-345

Patel A, Yamashita N, Ascaño M, Bodmer B, Boehm E, Bodkin-Clarke C, Ryu YK, and Kuruvilla R. RCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome. Nat Commun, 2015 Dec 14;6:10119.

Borden P, Houtz J, Leach SD, and Kuruvilla R. Sympathetic innervation during development is necessary for pancreatic islet architecture and functional maturation. Cell Rep 2013 Jul 25;4(2):287-301.

Ryu YK, Collins SE, Ho HY, Zhao H*, Kuruvilla R*. An autocrine Wnt5a-Ror signaling loop mediates sympathetic target innervation. Dev Biol 2013 May 1;377(1):79-89. *co-corresponding authors.

Chen SK, Chew KS, McNeill DS, Keeley PW, Ecker JL, Mao BQ, Pahlberg J, Kim B, Lee SC, Fox MA, Guido W, Wong KY, Sampath AP, Reese BE, Kuruvilla R*, Hattar S*. Apoptosis regulates ipRGC spacing necessary for rods and cones to drive circadian photoentrainment. Neuron 2013 Feb 6;77(3):503-15. *co-corresponding authors.

Ho HY, Susman MW, Bikoff JB, Ryu YK, Jonas AM, Hu L, Kuruvilla R, Greenberg ME. A Wnt5a-Ror-Dishevelled signaling pathway that controls embryonic tissue morphogenesis. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4044-51.

Bodmer B#, Ascaño M# and Kuruvilla R. Isoform-specific dephosphorylation of dynamin1 by calcineurin couples neurotrophin receptor endocytosis to axonal growth. Neuron 2011 Jun 23;70(6):1085-99. #Equal authors.

Armstrong A, Ryu Y-K, Chieco D and Kuruvilla R. Frizzled3 is required for neurogenesis and target innervation during sympathetic nervous system development. J Neurosci. 2011 Feb 16;31(7):2371-81.

Ascaño M, Richmond A, Borden P, and Kuruvilla R. Axonal targeting of Trk receptors via transcytosis regulates sensitivity to neurotrophin responses. J Neurosci. 2009 Sep 16;29(37):11674-85.

Bodmer B, Levine-Wilkinson S, Richmond A, Hirsh S and Kuruvilla R. Wnt5a mediates NGF-dependent axonal branching and growth in developing sympathetic neurons. J Neurosci. 2009 Jun 10;29(23):7569-81.