Keri Martinowich PhD

Lead Investigator, Lieber Institute for Brain Development; Associate Professor of Psychiatry and Neuroscience

Hill JL, Hardy NF, Jimenez DV, Maynard KR, Kardian AS, Pollock CJ, Schloesser, Martinowich K, "Loss of promoter IV-driven BDNF expression impacts oscillatory activity during sleep, sensory information processing and fear regulation", Translational Psychiatry, 6(8):e873, 2016.

Maynard KR, Hill JL, Calcaterra NE, Palko ME, Kardian A, Paredes D, Sukumar M, Adler BD, Jimenez DV, Schloesser RJ, Tessarollo L, Lu B, Martinowich K, "Functional role of BDNF production from unique promoters in aggression and serotonin signaling", Neuropsychopharmacology, 41(8), 1943-55, 2016.

Schloesser RJ, Orvoen S, Jimenez DV, Hardy NF, Maynard KR, Sukumar M, Manji HK, Gardier AM, David DJ, Martinowich K, “Antidepressant-like effects of electroconvulsive seizures require adult neurogenesis in a neuroendocrine model of depression”, Brain Stimulation, 8(5), 862-7, 2015.

Schloesser RJ, Jimenez DV, Hardy NF, Paredes D, Catlow BJ, Manji HK, McKay RD, Martinowich K, “Atrophy of pyramidal neurons and increased stress-induced glutamate levels in CA3 following chronic suppression of adult neurogenesis”, Brain Structure Function,219(3), 1139-48, 2014.

Sakata K, Martinowich K, Woo NH, Schloesser RJ, Jimenez DV, Ji Y, Shen L, Lu B, “Role of activity-dependent BDNF expression in hippocampal-prefrontal cortical regulation of behavioral perseverance”, PNAS, 110(37), 15103-8, 2013.

Tripp A, Oh H, Guilloux JP, Martinowich K, Lewis DA, Sibille E, “BDNF signaling and subgenual anterior cingulate cortex dysfunction in major depression”, American Journal of Psychiatry,169(11),1194-202, 2012.

Martinowich K, Schloesser RJ, Jimenez DV, Weinberger DR, Lu B, “Activity-dependent brain-derived neurotrophic factor expression regulates cortistatin-interneurons and sleep behavior”, Molecular Brain, 4(11), 2011.

Fritsch B, Reis J, Martinowich K, Schambra HM, Ji Y, Cohen LG, Lu B,  "Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning", Neuron, 66(2), 198-204, 2010.

Schloesser RJ, Manji HK, Martinowich K, "Suppression of adult neurogenesis leads to an increased hypothalamo-pituitary-adrenal axis response", NeuroReport, 20(6), 553-557, 2009.

Martinowich K, Hattori D, Wu H, Fouse S, He F, Hu Y, Fan G, Sun YE, "DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation", Science, 302(5646), 890-893, 2003.