King-Wai Yau PhD

Professor of Neuroscience

Do MT, Yau, KW (2013) Adaptation to steady light by intrinsically photosensitive retinal ganglion cells. Proc Natl Acad Sci USA [Epub ahead of print]

Pearson, R.A., Barber, A.C., Rizzi, M., Hippert, C., Xue, T., West, E.L., Duran, Y., Smith, A.J., Chuang, J.Z., Azam, S.A., Luhmann, U.F.O., Benucci, A., Sung, C.H., Bainbridge, J.W., Carandini, M., Yau, K.-W., Sowden, J.C. and Ali, R.R. Restoration of vision following transplantation of photoreceptors. Nature, in press.

Xue, T., Do, M.T.H., Riccio, A., Jiang, Z., Hsieh, J., Wang, H.C., Merbs, S.L., Welsbie, D.S., Yoshioka, T., Weissgerber, P., Stolz, S., Flockerzi, V., Freichel, M., Simon, M.I., Clapham, D.E. and Yau, K.-W. (2011). Melanopsin signaling in mammalian iris and retina. Nature 479:67-73.

Luo DG, Yue WW, Ala-Laurila P, Yau K.-W. (2011) Activation of visual pigments by light and heat. Science 332(6035):1307-12.

Cheng, N., Tsunenari, T. and Yau, K.-W. (2009). Intrinsic light sensitivity of retinal horizontal cells of teleosts. Nature 460, 899-903.LINK

Do, M.T.H., Shin, S.H., Xue, T., Zhong, H., Liao, H.-W., Bergles, D.E. and Yau, K.-W. (2009). Photon capture and signaling by melanopsin retinal ganglion cells. Nature 457, 281-287.LINK

Fu, Y., Kefalov, V., Luo, D.-G., Xue, T. and Yau, K.-W. (2008). Quantal noise from human red cone pigment. Nature Neurosci. 11, 565-571.LINK

Su, C.-Y., Luo, D., Terakita, A., Shichida, Y., Liao, H.-W., Kazmi, M.A., Sakmar, T.P. and Yau, K.-W. (2006). Parietal-eye phototransduction components and their potential evolutionary implications. Science 311, 1617-1621.LINK

Bhandawat, V., Reisert, J. and Yau, K.-W. (2005). Elementary response of olfactory receptor neurons to odorants. Science 308, 1931-1934.LINK

Kefalov, V.J., Estevez, M.E., Kono, M., Goletz, P.W., Crouch, R.K., Cornwall, M.C. and Yau, K.-W. (2005). Breaking the covalent bond – a pigment property contributing to desensitization in cones. Neuron 46, 879-890.

Dacey, D.M., Liao, H.-W., Peterson, B.B., Robinson, F.R., Smith, V.C., Pokorny, J., Yau, K.-W. and Gamlin, P.D. (2005). Melanopsin-expressing ganglion cells in primate retina signal color and irradiance and project to the LGN. Nature 433, 749-754.LINK

Reisert, J., Lai, J., Yau, K.-W and Bradley, J. (2005). Na+-K+-2Cl- cotransporter NKCC1 is necessary for the excitatory Cl- response of mouse olfactory receptor neurons. Neuron 45, 553-561.

Kefalov, V., Fu, Y., Marsh-Armstrong, N. and Yau, K.-W. (2003). Role of visual pigment properties in rod and cone phototransduction. Nature 425, 526-531.LINK

Zhong, H., Molday, L.L., Molday, R.S. and Yau, K.-W. (2002). The heteromeric cyclic nucleotide-gated channel adopts a 3A:1B stoichiometry. Nature 420, 193-198.LINK

Hattar, S., Lucas, R.J., Mrosovsky, N., Thompson, S., Douglas, R.H., Hankins, M.W., Lem, J., Biel, M., Hofmann, F., Foster, R.G. and Yau, K.-W. (2003). Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice. Nature 424, 76-81.LINK

Sun, H., Tsunenari, T., Yau, K.-W. and Nathans, J. (2002). Bestrophin, the protein product of the vitelliform macular dystrophy gene, defines a new family of chloride channels. Proc. Natl. Acad. Sci. USA 99, 4008-4013.Link

Hattar, S., Liao, H-S, Takao, M., Berson, D.M. and Yau, K-W. (2002) Melanopsin-containing retinal ganglion cells: architecture, projections and intrinsic photosensitivity. Science 295, 1065-1070. PubMed Abstract