Bin Wu Ph.D.

Assistant Professor of Biophysics and Biophysical Chemistry

Blake L, Wu, B., One message, many translation: heterogeneity revealed with multicolor imaging, Mol Cell, 2019, DOI: 10.1016/j.molcel.2019.06.026

Sato H, Wu, B., Delahaye F, Singer RH, Greally JM, Retargeting of macroH2A following mitosis to cytogenetic-scale heterochromatin domain, J Cell Biol, 2019, DOI: 10.1083/jcb.201811109, PMID:3111057

Latallo M, Livingston N, Wu, B., Translation imaging of single mRNAs in established cell lines and primary cultured neurons, Methods, 2019, DOI:10.1016/j.ymeth.2019.03.021

Adviarahan S., Livingston N, Nicholoson B, Rahman S, Wu, B., Rissland O and Zenklusen D, Spatial organization of single mRNAPs at different stages of the gene expression pathway, Mol Cell, 2018, DOI: 10.1016/j.molce.2018.10.010.

Biswas J.*, Liu Y.*, Singer, RH, Wu, B., Fluorescence imaging methods to investigate translation in single cells, Cold Spring Harbor Perspective, 2018, DOI: 10.1101/cshperspect.a032722

Tutucci, E., Livingston, NM., Singer, RH, Wu, B., Imaging mRNA in vivo, from birth to death, Annu. Rev. Biophys., 2018, DOI: 1146/annurev-biophys-070317-033037

Donnelly, S., Cabrera, R., Mao, S., Christin, J., Wu, B., Guo, W., Bravo-Cordero J., Condeelis J., Segall J., and Hodgson L., Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation, J. Cell Biol., 2017, DOI:10.1083/jcb.201704048

Bin Wu, Eliscovich C, Yoon Y and Singer R.H., Translation dynamics of single mRNAs in live cells and neurons, Science, Vol 352, Issue 6292, 2016, pp. 1430-1435, DOI:10.1126/science.aaf1084

Bin Wu,. Buxbaum A.R., Katz Z, Yoon, Y and Singer R.H, Quantifying protein-mRNA interactions in single live cells, Cell, 2015, 162 (1): 211-220, PMID 26140598 / PMCID: PMC4491145

Yoon Y.J.*, Bin Wu*, Buxbaum A.R., Sulagna D, Tsai A, English B.P., Grimm J.B., Lavis D.L. and Singer R.H., Glutamate-induced RNA localization and translation in neurons, Proceedings of National Academy of Science, 2016, in press

Bin Wu*, Miskolci, V*, Sato H., Tutucci E., Kenworthy C.A., Donnelly S.K., Yoon Y.J., Cox, D, Singer R.H. and Hodgson L., Synonymous modification results in high fidelity gene expression of repetitive protein and nucleotide sequences, Genes & Developments, 2015, 29 (8): 876-886, PMID: 25877922 / PMCID: PMC4403262 (*equal contribution)