Elisabeth Glowatzki PhD

Professor of Otolaryngology Head and Neck Surgery and Neuroscience

Selected Publications (of 48)                                            

1. Glowatzki E, Fuchs PA. Cholinergic synaptic inhibition of inner hair cells in the neonatal mammalian cochlea. Science 2000; 288: 2366-2368.

2. Glowatzki E, Fuchs PA. Transmitter release at the hair cell ribbon synapse. Nature Neuroscience 2002; (5)2:147-154.

3. Katz E, Elgoyhen AB, Gómez-Casati ME, Knipper M,Vetter DE, Fuchs PA, Glowatzki E. Developmental regulation of nicotinic synapses on cochlear inner hair cells. Journal Neuroscience 2004; 24(36):7814-7820.

4. Pyott S, Glowatzki E, Trimmer J, Aldrich R. Extrasynaptic localization of inactivating BK channels in mouse inner hair cells. Journal Neuroscience 2004; 24(43):9469-9474.

5. Goutman JD, Fuchs PA, Glowatzki E. Facilitating efferent inhibition of inner hair cells in the cochlea of the neonatal rat. Journal of Physiology 2005; 566.1:49-59.

6. Glowatzki E, Chen N, Hiel H, Jin L, Yi E, Tanaka K, Ellis-Davies JCR, Rothstein JD, Bergles DE. The glutamate-aspartate transporter (GLAST) mediates glutamate uptake at inner hair cell afferent synapses in the mammalian cochlea. Journal of Neuroscience 2006; 26(29):7659-7664.

7. Goutman JD, Glowatzki E, Time course and calcium dependence of transmitter release at a single ribbon synapse. PNAS 2007; 104 (41):16341-16346.

8. Tritsch NX, Yi E, Gale JE, Glowatzki E, Bergles DE. The origin of spontaneous activity in the developing auditory system. Nature 2007, 450:50-55.

9. Seal, RP, Akil O, Yi E, Weber CM, Grant L, Yoo J, Clause A, Kandler K, Noebels JL, Glowatzki E, Lustig LR, Edwards RH. Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3. Neuron 2008, 57(2):263-75. 

10. Martinez-Monedero R, Yi E, Oshima K, Glowatzki E, Edge ASB. Differentiation of inner ear stem cells to functional sensory neurons. Developmental Biology 2008; 68(5):669-84.
11. Weisz C, Glowatzki E, Fuchs P. The postsynaptic function of type II cochlear afferents. Nature 2009; 461(7267):1126-9.

12. Grant L, Yi E, Glowatzki E. Two modes of release shape the postsynaptic response at the inner hair cell ribbon synapse. Journal of Neuroscience 2010; 30(12):4210-4220.

13. Yi E, Roux I, Glowatzki E. Dendritic HCN channels shape excitatory postsynaptic potentials at the inner hair cell afferent synapse in the mammalian cochlea. Journal of Neurophysiology 2010; 103(5):2532-43.

14. Goutman JD, Glowatzki E. Short-term facilitation modulates size and timing of the synaptic response at the inner hair cell ribbon synapse. Journal of Neuroscience 2011; 31(22):7974-81. PMCID: PMC3125715.

15. Roux I, Wersinger E, McIntosh JM, Fuchs PA, Glowatzki E. Onset of cholinergic efferent synaptic function in sensory hair cells of the rat cochlea. Journal of Neuroscience 2011; 31(42):15092-101. PMCID: PMC3213862.

16. Weisz CJC, Lehar M, Hiel H, Glowatzki E, Fuchs PA. Synaptic Transfer from Outer Hair Cells to Type II Afferent Fibers in the Rat Cochlea. Journal of Neuroscience 2012; 32(28):9528-9536.

17. Korrapati S, Roux I, Glowatzki E, Doetzlhofer A. Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea. PLoS One 2013; 8(8):e73276.

18. Weisz CJC, Glowatzki, E, Fuchs, P. Excitability of Type II Cochlear Afferents. Journal of Neuroscience 2014; 34(6):2365-2373.

19. Sadeghi, SG, Pyott SJ, Yu Z, Glowatzki E. Glutamatergic signaling at the vestibular hair cell calyx synapse. Journal of Neuroscience, 2014;34(44):14536-14550.

20. Liu C, Glowatzki E, Fuchs PA. Unmyelinated type II afferent neurons report cochlear damage. Proc Natl Acad Sci USA 2015;112(47):14723-14727.

21. Roux I, Wu JS, McIntosh, JM, Glowatzki E. Assessment of the expression and role of the α1 nAChR subunit in efferent cholinergic function during the development of the mammalian cochlea. Journal of Neurophysiology 2016; 116(2):479-92. PMCID: PMC4978794.

22. Martinez-Monedero R, Liu C, Weisz C, Vyas P, Fuchs PA, Glowatzki E. GluA2-Containing AMPA Receptors Distinguish Ribbon-Associated from Ribbonless Afferent Contacts on Rat Cochlear Hair Cells. eNeuro. 2016; 12:3(2). PMCID:PMC4874539.

23. Wu JS, Young ED, Glowatzki E. Maturation of Spontaneous Firing Properties after Hearing Onset in Rat Auditory Nerve Fibers: Spontaneous Rates, Refractoriness, and Interfiber Correlations. J Neurosci. 2016; 12:36(41):10584-10597. PMCID: PMC5059429.

24. Vyas P, Wu JS, Zimmerman A, Fuchs P, Glowatzki E. Tyrosine Hydroxylase Expression in Type II Cochlear Afferents in Mice. J Assoc Res Otolaryngol. 2017; 18(1):139-151. PMCID: PMC5243262.

25. Ye Z, Goutman JD, Pyott SJ, Glowatzki E. mGluR1 enhances efferent inhibition of inner hair cells in the developing rat cochlea. J Physiol 2017; 595(11):3483-3495. PMCID: PMC5451706.
26. Wu JS, Vyas P, Glowatzki E, Fuchs PA. Opposing expression gradients of calcitonin-related polypeptide alpha (Calca/Cgrpa) and tyrosine hydroxylase (Th) in type II afferent neurons of the mouse cochlea. J Comp Neurol. 2018 526(3):425-438.

27. Vyas P, Wu JS, Jimenez A, Glowatzki E, Fuchs PA. Characterization of transgenic mouse lines for labeling type I and type II afferent neurons in the cochlea. Scientific Reports 2019, 9, Article number: 5549. PMCID: PMC6447598.